MUSE pricing is tiered based on the World Bank World Development Indicators, recognizing the unique needs of libraries in economically disadvantaged countries. In addition, Project MUSE participates in INASP, a program that works to make book and journal content more widely available to libraries in developing countries. This organization helps MUSE's mission-driven publishers reach new audiences with their content in places they might not be able to reach on their own. For Project MUSE, the focus with INASP is the low-income countries of sub-Saharan Africa and Central America, although INASP's membership is much broader than just these two regions.

A variety of book products, journal products, and #other products are currently offered for international academic libraries (outside of the USA and Canada).